John Gruber blogged a comparison with Apple losing Steve Jobs:

I argued, on the day of his resignation, that Apple was likely to continue to thrive post-Jobs, writing, “Jobs’s greatest creation isn’t any Apple product. It is Apple itself.” He built a great company with a deep bench and a highly distinctive, incredibly strong culture.

Steve Jobs knew he was dying and prepared for it. Until this week, Jensen Huang thought he was going to lead Nvidia for another decade or longer. Getting rid of him so suddenly is going to have aftershocks.